Glucagon-like peptide 1 (1-37), human TFA
CAS No.
Glucagon-like peptide 1 (1-37), human TFA ( HuGLP-1 TFA )
Catalog No. M29846 CAS No.
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product NameGlucagon-like peptide 1 (1-37), human TFA
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NoteResearch use only, not for human use.
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Brief DescriptionGlucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon.
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DescriptionGlucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon. (In Vitro):Glucagon-like peptide-1 (GLP-1) is produced by the posttranslational processing of proglucagon and acts as a regulator of various homeostatic events. GLP-1(1-37) is more stable than GLP-1(7-37), with 94.7% of the initial amount of peptide left after a 4h exposure to mouse serum. GLP-1(1-37) is confirmed to be a highly potent agonist of the GLP-1 receptor (GLP-1R) by measuring the expression of the luciferase reporter gene expression in transiently transfected human embryonic kidney (HEK293) cells.(In Vivo):GLP-1(1–37) decreases glycemic excursion in a dose-dependent. The administration of GLP-1(1–37) or GLP-1(7–37) markedly decrease blood glucose levels at 15 min and 30 min compared with the control group.
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SynonymsHuGLP-1 TFA
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PathwayOthers
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TargetOther Targets
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RecptorGLP-1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight4283.5
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Molecular FormulaC188H276N51F3O61
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Zhao L, et al. Glucagon-like peptide-1(1-37) can enhance blood glucose homeostasis in mice. Regul Pept. 2012 Oct 10;178(1-3):1-5.
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